The Genomic Landscape of HIV-Associated Plasmablastic Lymphoma
نویسندگان
چکیده
منابع مشابه
Current knowledge on HIV-associated Plasmablastic Lymphoma
HIV-associated PBL is an AIDS-defining cancer, classified by WHO as a distinct entity of aggressive DLBCL. To date less than 250 cases have been published, of them 17 are pediatric. The pathogenesis of this rare disease is related to immunodeficiency, chronic immune stimulation and EBV. Clinically is a rapid growing destructive disease mainly involving the oral cavity even if extraoral and extr...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 25-year-old man without any relevant medical history was admitted to our hospital for progressive weakness, fever, night sweats, and weight loss. Physical examination showed several round skin nodules and multiple painless lymph nodes in the axillary and i...
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Plasmablastic lymphoma (PBL) is a rare B-cell lymphoma occurring mainly in HIV patients. The tumor frequently involves extranodal sites such as the oral cavity, nasal cavity, gastrointestinal tract, skin, and lungs. The neoplastic cells are characterized by a plasmablastic appearance and typical immunophenotype that indicates plasma cell differentiation. Herein, we report a case of intraocular ...
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BACKGROUND Plasmablastic lymphoma (PBL) is a B-cell malignancy associated with human immunodeficiency virus (HIV). PBL could also influence the HIV-negative patients. The study aimed to identify prognostic factors for survival among Chinese PBL patients. MATERIALS AND METHODS Eligible patients from literature and Peking Union Medical College Hospital (PUMCH) were included in this study. Clini...
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ژورنال
عنوان ژورنال: Blood Cancer Discovery
سال: 2020
ISSN: 2643-3230,2643-3249
DOI: 10.1158/2643-3249.bcd-20-0075